Melanotan-I

Melanotan I (Afamelanotide) – Research Peptide

Melanotan I (Afamelanotide) is a synthetic analogue of α‑Melanocyte Stimulating Hormone (α‑MSH), supplied as a lyophilized reagent for in vitro research into MC1R melanocortin receptor activation, pigmentation signalling pathways, and cellular oxidative response models.

Melanotan I (also referenced as Afamelanotide) is a synthetic research peptide derived from α‑Melanocyte Stimulating Hormone (α‑MSH). In laboratory settings, it is employed to examine the activation of melanocortin receptors—particularly MC1R—in the context of pigmentation pathway analysis, oxidative response profiling, and signal transduction studies conducted under in vitro conditions.

Melanotan I is manufactured to rigorous laboratory standards and verified by High‑Performance Liquid Chromatography (HPLC), achieving a confirmed purity of ≥99%. This compound is suitable for use in controlled biochemical and pharmacological assays involving receptor activation and peptide signalling models.

Key Specifications

• Name: Melanotan I (Afamelanotide)

• Molecular Formula: C78H111N21O19

• Molecular Weight: ≈1646.9 Da

• Form: Lyophilized Powder

• Purity: ≥99% (HPLC verified)

• Storage: Store refrigerated; protect from light and moisture

• Shelf Life: Sealed lyophilizate. Shelf life 24 months from manufacture.

Research Applications

• Studied in the context of melanocortin MC1R receptor signalling in cell-based assay systems.

• Referenced in investigations into pigmentation pathway regulation, oxidative response, and peptide-based signalling.

• Used as a reference reagent in biochemical and pharmacological receptor binding studies.

• Lyophilized format supports stable, reproducible in vitro research conditions.

A batch-specific Certificate of Analysis (CoA) is available on request and accompanies every order.