5-Amino-1MQ

5-Amino-1MQ is a high-purity small-molecule research compound supplied as a stable lyophilized powder. It is characterised by its selective interaction with NNMT (Nicotinamide-N-Methyltransferase), an enzyme implicated in a range of metabolic and biochemical regulatory processes, making it a valuable reference compound for preclinical and in-vitro research programmes. Each vial is supplied with a purity exceeding 98%, with a molecular formula of C₁₂H₁₁N₅ and a molecular weight of 225.25 g/mol.

Research background

5-Amino-1MQ has been investigated in preclinical models as a selective inhibitor of NNMT, an enzyme that catalyses the methylation of nicotinamide and has been referenced in the literature in connection with cellular energy metabolism, NAD⁺-associated signalling pathways, and energy homeostasis. In-vitro studies have applied this compound in the context of enzymatic regulation and biochemical signalling, with particular attention to NNMT's reported role in metabolic tissue biology. As with all compounds in this category, findings remain within the scope of controlled laboratory research.

Reconstitution & handling

5-Amino-1MQ is supplied as a lyophilized powder and should be reconstituted with an appropriate volume of bacteriostatic water (BAC water) prior to use. Add the BAC water slowly to the vial and swirl gently until the powder is fully dissolved — do not shake, as this may compromise compound integrity. All reconstitution and handling should be performed under suitable aseptic laboratory conditions.

Storage & stability

The lyophilized powder should be stored in a cool, dry environment, protected from light and moisture. Refrigerated or frozen storage is recommended to maximise shelf stability. Once reconstituted, the solution should be kept refrigerated and used within a short, defined window in accordance with standard laboratory practice for research-grade compounds.

A batch-specific Certificate of Analysis (CoA) is included with every order, confirming purity and compound identity.