CJC-1295 with DAC

CJC-1295 with DAC is a synthetic Growth Hormone–Releasing Hormone (GHRH) analogue incorporating a Drug Affinity Complex (DAC) modification, which significantly extends the peptide's circulating half-life compared to unmodified GHRH analogues. Supplied as a lyophilized powder, it is intended for use as a biochemical research reagent in controlled laboratory settings. Purity is verified at ≥99% by HPLC, and the molecular formula is C₁₆₅H₂₇₁N₄₇O₄₆ (molecular weight ≈ 3647.1 Da).

Research background

CJC-1295 with DAC has been studied in the context of GHRH receptor activation and the downstream stimulation of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) release. Its DAC modification has been investigated as a means of prolonging receptor engagement, making it a reference compound of interest in endocrinological and receptor signalling research. The extended half-life characteristic of this analogue has been referenced in studies exploring the regulation and kinetics of growth hormone secretion under sustained GHRH receptor stimulation, as well as in broader in-vitro biochemical research programmes examining hypothalamic–pituitary axis signalling.

Reconstitution & handling

The lyophilized powder should be reconstituted using bacteriostatic water (BAC water). Add an appropriate volume of BAC water directly to the vial and gently swirl until the powder is fully dissolved — do not shake, as this may compromise peptide integrity. All handling should be carried out under aseptic conditions using appropriate laboratory equipment.

Storage & stability

• Store the lyophilized product refrigerated and protected from light and moisture. For extended storage, freezing is recommended.
• Once reconstituted, keep the solution refrigerated at 2–8 °C and use within a short timeframe to maintain integrity.
• Avoid repeated freeze–thaw cycles after reconstitution.

Each order is accompanied by a batch-specific Certificate of Analysis (CoA) confirming identity and purity.