Glutathione

Glutathione (GSH) is a naturally occurring tripeptide composed of three amino acids — glutamate, cysteine, and glycine — and represents one of the most extensively characterised small molecules in cellular biochemistry. Purity Base supplies Glutathione as a high-purity lyophilised powder (≥98%, HPLC-verified), with a molecular formula of C10H17N3O6S and a molecular weight of 307.32 Da, manufactured to strict laboratory standards for use as a biochemical research reagent.

Research background

Glutathione has been studied extensively in preclinical and in vitro settings for its central role in redox biology. Key areas of investigation include:

• Models of oxidative stress and antioxidant defence, where GSH is investigated as a primary intracellular reducing agent.
• Preclinical studies focused on cellular detoxification and redox regulation, including conjugation reactions mediated by glutathione S-transferases.
• In vitro research into mitochondrial function, enzyme activity, and cell protection mechanisms, where GSH status is referenced as a key experimental variable.
• Biochemical assays examining the interplay between the reduced (GSH) and oxidised (GSSG) forms as an indicator of cellular redox balance.

Reconstitution & handling

This product is supplied as a lyophilised powder and should be reconstituted with bacteriostatic water (BAC water) prior to use. Add an appropriate volume of BAC water directly to the vial and gently swirl until the powder is fully dissolved. Do not shake the vial, as this may compromise the integrity of the compound. Handle under clean laboratory conditions and keep the reconstituted solution cold at all times when not in active use.

Storage & stability

Store the lyophilised product refrigerated, protected from light and moisture. Once reconstituted, keep the solution refrigerated and use within a short window to ensure compound integrity and reproducibility of results. Avoid repeated freeze-thaw cycles.

Every order is accompanied by a batch-specific Certificate of Analysis (CoA) confirming identity, purity, and compliance with quality specifications.