Melanotan-II

Melanotan-II is a synthetic research peptide structurally derived from α-Melanocyte Stimulating Hormone (α-MSH), supplied by Purity Base as a lyophilized powder verified at ≥99% purity by HPLC. With a molecular formula of C50H69N15O9 and a molecular weight of approximately 1024.18 Da, it is intended exclusively for controlled biochemical and pharmacological research in in vitro models.

Research background

Melanotan-II has been investigated extensively in the literature for its activity at melanocortin receptors, particularly MC1R and MC4R. Research has examined its role as a tool compound for studying pigmentation pathways, energy homeostasis, and cellular signalling mechanisms. It has also been referenced in studies probing neuronal signalling cascades and receptor activation kinetics in controlled laboratory settings. All findings cited in the literature pertain to in vitro and preclinical research contexts.

Reconstitution & handling

Melanotan-II is supplied as a lyophilized powder and should be reconstituted with an appropriate volume of bacteriostatic water (BAC water) prior to use. Add the BAC water slowly and gently swirl the vial until the powder is fully dissolved — do not shake, as vigorous agitation may degrade the peptide. Handle all solutions on ice or at reduced temperature and use sterile technique throughout.

Storage & stability

The lyophilized powder should be stored refrigerated and protected from light and moisture. For extended periods, storage at −20 °C is recommended. Once reconstituted, the solution should be kept refrigerated and used within a short timeframe to maintain integrity. Avoid repeated freeze–thaw cycles.

Every order is accompanied by a batch-specific Certificate of Analysis (CoA) confirming compound identity and HPLC-verified purity.