PT-141

PT-141 (Bremelanotide) is a synthetic lyophilized research peptide derived from α-Melanocyte Stimulating Hormone (α-MSH). Supplied as a 10 mg vial of lyophilized powder, it is produced to rigorous laboratory standards and verified by High-Performance Liquid Chromatography (HPLC) to a purity of ≥99%, making it a reliable reference compound for receptor-targeted peptide research.

Research background

PT-141 has been studied extensively in the context of melanocortin receptor activity, with particular focus on the MC3R and MC4R receptor subtypes. In in vitro and preclinical research models, it has been investigated for its role in melanocortin signaling pathways, neuroendocrine regulation, and neurotransmitter modulation. The compound has also been referenced in the literature exploring energy balance, neural activation, and receptor pharmacology, as well as broader studies into peptide-based biochemical signalling mechanisms.

Reconstitution & handling

PT-141 is supplied as a lyophilized powder and should be reconstituted with an appropriate volume of bacteriostatic water (BAC water) prior to use. Add the BAC water slowly to the vial and swirl gently until the powder is fully dissolved — do not shake. Once reconstituted, handle the solution with care and keep it cold throughout use. Standard aseptic technique is recommended at all stages of preparation.

Storage & stability

The lyophilized product should be stored refrigerated and protected from light and moisture. Long-term storage in a freezer is advised to preserve maximum stability. Once reconstituted, the solution should be kept refrigerated and used within a short timeframe to maintain integrity. Avoid repeated freeze-thaw cycles.

A batch-specific Certificate of Analysis (CoA) accompanies every order, providing full documentation of purity and quality testing.