Reta

Reta (LY-3437943) is a potent synthetic peptide engineered for advanced biochemical and metabolic research. Composed of 39 amino acids and exhibiting an exceptional purity of ~99.3%, this triple receptor agonist is specifically designed to activate GLP-1, GIP, and glucagon receptors—key regulators studied in the context of energy balance, lipid metabolism, and glucose homeostasis.

As a research reagent, Reta is referenced in preclinical in vitro studies examining metabolic pathway modulation, energy expenditure, and related biochemical mechanisms. Its triple-agonist profile offers a model for exploring synergistic signalling across three receptor pathways, extending beyond dual-agonist reference compounds.

A batch-specific Certificate of Analysis (CoA) accompanies every order and is available on request. The CoA includes HPLC and mass spectrometry data for full analytical transparency and traceability.

Key Specifications

• Purity: ~99.3% (HPLC verified — CoA available)

• Molecular Formula / Weight: C221H342N46O68 / 4,731.33 Da

• Amino Acid Sequence: Fully documented in CoA

• Testing Lab: Janoshik Independent Peptide Analytics

• Analytical Methods: HPLC and Mass Spectrometry

• Form: Lyophilized Powder

• Storage: Refrigerated; protect from light and moisture

• Shelf life: Sealed lyophilizate. Shelf life 24 months from manufacture.

Research Applications

• Triple-agonist profile supports comprehensive in vitro exploration of glucose regulation, satiety signalling, and lipid metabolism pathways.

• Used as a reference reagent in studies examining mechanisms associated with obesity models, type 2 diabetes research frameworks, and energy homeostasis.

• Enables multi-pathway activation studies extending beyond dual-agonist reference models.

• Supported by independent third-party verification and transparent analytical data.