SEMAX

Semax is a synthetic heptapeptide and a structurally derived analogue of ACTH (Adrenocorticotropic Hormone). Supplied as a lyophilized powder at 10 mg per vial, it is verified by High-Performance Liquid Chromatography (HPLC) to a purity of ≥99%. Its well-defined molecular profile — molecular formula C₃₇H₅₁N₉O₁₀, molecular weight 751.86 g/mol — makes it a reliable reference compound for controlled neurobiological and biochemical research programmes.

Research background

Semax has been extensively investigated in the context of central nervous system research. It has been studied in relation to neuroprotective mechanisms, with the literature referencing its potential role in models of neurological stress and neural resilience. Research has also examined its influence on cognitive and memory-associated pathways, as well as processes linked to attention, brain plasticity, and mood regulation. Separately, Semax has been referenced in stress-adaptation models, where its structural relationship to ACTH fragments has made it a compound of interest for investigators studying HPA-axis-related signalling in controlled, in-vitro conditions.

Reconstitution & handling

Semax is supplied as a lyophilised powder and should be reconstituted with bacteriostatic water (BAC water) prior to use. Add an appropriate volume of BAC water directly to the vial, then gently swirl until the powder is fully dissolved — do not shake, as this may degrade peptide integrity. Handle reconstituted solution with care and keep cold at all times. Use sterile technique throughout.

Storage & stability

The lyophilised powder should be stored refrigerated or frozen, protected from light and moisture. Once reconstituted, the solution should be kept refrigerated (2–8 °C) and used within a short period. Avoid repeated freeze-thaw cycles, which may compromise compound integrity.

Every order of Semax is accompanied by a batch-specific Certificate of Analysis (CoA), confirming purity and identity as verified by HPLC.