Snap-8

Snap-8 (Acetyl Octapeptide-3) is a synthetic eight-amino-acid peptide supplied as a lyophilized powder of verified high purity. Developed as a structural extension of Acetyl Hexapeptide-8 (Argireline), it carries a molecular formula of C₄₅H₆₈N₁₄O₁₂ and a molecular weight of approximately 888.1 Da, with purity confirmed at ≥99% by HPLC. Its refined chain length confers improved stability relative to shorter peptide analogues, making it a well-characterised reference compound for biochemical and dermatological research programmes.

Research background

Snap-8 has been studied in the context of SNARE complex protein interactions — the molecular machinery involved in vesicle docking and neurotransmitter release at the neuromuscular junction. It has been investigated as a model compound in research examining neuromuscular signalling pathways, muscle contraction dynamics, and the mechanisms underlying skin aging and loss of tissue tension. The literature has referenced its structural resemblance to endogenous SNARE-associated sequences as a basis for probing signal transduction cascades in both in vitro cellular models and biochemical assay systems.

Reconstitution & handling

Snap-8 is presented as a lyophilised powder and should be reconstituted with an appropriate volume of bacteriostatic water (BAC water) prior to use. Add the BAC water slowly to the vial, then gently swirl — do not shake — until the powder is fully dissolved. Avoid vigorous agitation, which may compromise peptide integrity. Handle under clean laboratory conditions and keep the reconstituted solution cold at all times.

Storage & stability

The lyophilised product should be stored refrigerated and protected from light and moisture. Once reconstituted, the solution should be kept refrigerated and used within a short period to preserve activity and prevent degradation. Repeated freeze–thaw cycles of the reconstituted solution should be avoided.

A batch-specific Certificate of Analysis (CoA) confirming purity and identity by HPLC accompanies every order.